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Sylvain Doré

Sylvain Doré

Professor of Neurology and Psychiatry; Investigator, McKnight Brain Institute and CTRND
University of Florida


Sylvain Doré, PhD is a Professor and Program Director of Research Operations in the Department of Anesthesiology, as well as Professor of Neurology, Psychiatry, Pharmaceutics, and Neuroscience, at the University of Florida, College of Medicine. Dr. Doré attained his PhD, in biomedical science, from the University of Montreal and an MS degree in pharmacology at the University of Quebec. He received post-PhD training in psychiatry at McGill University, as well as post-PhD training in neuroscience at Johns Hopkins University. Dr. Doré’s research pertains to studying new effective mechanisms that limit neuronal dysfunction associated with ischemic and hemorrhagic stroke, Alzheimer disease (AD), aging, and various other neurological disorders. His objective is focused on understanding the protective role of heme metabolites in the brain using cellular/molecular techniques and various models of stroke, Alzheimer disease, and aging. New knowledge is gained specifically, by investigating the action and the role of activity of the heme oxygenase enzyme and its unique bioactive metabolites, namely, carbon monoxide, iron, biliverdin, and bilirubin. His overall goal is to slow down the progression of the disease, and ultimately stop it.

Research Interest

Neurodigenerative disorders, ischemic stroke, Alzheimer’s disease, aging, heme oxygenase, prostaglandins