Surbhi Chaturvedi
Mahatma Gandhi Medical College & Hospital, India
Title: Stroke in young: rare associations
Biography
Biography: Surbhi Chaturvedi
Abstract
The issue of stroke in young in the world has long been of interest to the neurologists. Though the traditional risk factors of stroke play a significant role in young age group also, the presence of high number of cryptogenic strokes, cardio-embolic and venous strokes makes diagnostic evaluation in this age group more challenging. Here, we report 2 cases of young patients with stroke as a rare manifestation of vasculitis and emphasize the need for thourough evaluation of young patients with stroke to establish the underlying etiology. Our 1st patient was a young female of 35 years with recurrant stroke (2 episodes till now and this time 2nd episode), presented with few episodes of TIA followed by aphasia and right hemiparesis with skin lesions in form of livedo retucularis and digital infarction and 1 episode of left focal seizure. MRI was suggestive of infarcts in different stages both acute and chronic in different vascular distribution. Possibility of vasculitis and embolic event was there. Skin biopsy was suggestive of Sneedon syndrome that matched our clinical presentation as well. Our 2nd patient was a young female of 13 years with young onset acute right hemiplegia, global aphasia with absent left carotid, brachial and radial pulse. MRI brain was suggestive of acute infarct in left MCA territory. CT angiography showed significant stenosis(80-90%) at the origin of left CCA and subclavian artery. ESR, CRP, ANA and anticardiolipin antibody was positive. So she was diagnosed to have Takayasu arteritis with APLA syndrome. Total 9 cases of TA with APS have been reported as yet.