Eduardo Flores Alvarez
National Autonomous University of Mexico, Mexico
Title: Advantage of endoscopic surgical technique for resection of pituitary adenoma with suprasellar extension: first series of the General Hospital of Mexico
Biography
Biography: Eduardo Flores Alvarez
Abstract
Background: Pituitary adenoma is the most common tumor in the sella turcica and constitutes 10-15% of the intracranial neoplasms, making them the third most common primary brain tumor in adults after meningiomas and gliomas. It is estimated that between 20 and 25% of the general population could have small hypophyseal tumors without symptoms. Aim: Our retrospective study carried out in the General Hospital of Mexico, Mexico city aimed to determine the advantage of endoscopic endonasal approach for surgical treatment of pituitary adenomas with suprasellar extension. Methodology: A series of 48 patients from December 2014 to December 2017 including patients from 18-75 years old were operated using an endoscopic endonasal approach, measurement of size, extension and invasion was performed based on the Knops and Wilson Hardy classification in the pre-operative and in the post-operative period using magnetic resonance imaging, endocrinological evaluations were performed in addition to the visual function evaluations, post-surgical complications were also documented. Evaluation of the volume of resection is done by comparing the pre-operative and post-operative magnetic resonance studies. Results: Of the total 48 patients less than 30% have non-functioning pituitary adenomas, study groups were comprising patients with surgical resection greater than 80%, resection between 50-80% and patients with resection less than 50% resulting respectively 73%, 22% and 5%. Only one deaths occurred and no group differences were noted in the post-operative complications (p=0.021). The endoscopic endonasal approach is safe, improving vision, illumination and degree of resection in the case of adenomas with supraselar extension.